Beni-Suef University, National Institute of Longevity Elderly Sciences
NILES journal for Geriatric and Gerontology
2636-3224
2636-3232
4
Geriatric Ophthalmology
2021
04
01
The effect of cigarette smoking on choroidal vasculature measured by Optical Coherence Tomography Angiography (OCTA)
1
18
EN
Ebtsam
Saber
Ophthalmology department, Faculty of medicine ,BeniSuef university , Egypt
ebtsammostafa91@yahoo.com
Mohamed Yasser
Sayed
SAIF
0000-0002-2376-2222
Ophthalmology department , Faculty of Medicine , Beni-Suef University
ysaif@med.bsu.edu.eg
Moustafa
Abd-Elnaby
Saeed
0000-0002-5783-7333
Department of Ophthalmology, Beni-Suef University
dr.mostafaan.2014@gmail.com
10.21608/niles.2020.46466.1039
Background: Cigarette smoking has been associated with low blood velocity of ophthalmic artery, while systolic blood pressure has been positively correlated with velocities in the ophthalmic artery and the central retinal artery. These effects are the result of interaction of nicotine-induced peripheral vasoconstriction and vasodilation caused by carbon monoxide in smokers. OCTA is a novel, noninvasive scanning technology which allow visualizing of the retinal and choroidal circulation. It permits assessing the retinal vasculature layer by layer and allows physicians to take images of the deep capillary plexus with no dye injection.<br />Methods: retrospective case control study included 100 participants (50 smokers and 50 healthy nonsmokers) recruited from Ophthalmology Department in Beni -Suef University Hospital. Participants were equally divided into two groups: Group (1): Included 50 smokers otherwise healthy. Group (2): Included 50 normal subjects (nonsmokers) used as control. Both groups underwent OCTA study.<br />Results: A highly significant statistical difference between both groups regarding smoking duration, while age and gender were of no significant. No statistical difference between both groups regarding perfusion within retinal layers between both groups as recorded in whole image. Age, IOP and neovascularization were positively, correlated with duration of smoking, perfusion and choroidal thicknesses in all areas were negatively correlated with duration of smoking. <br />Conclusion: We did not find a significant difference in choroidal blood flow, vessel density, or choroidal thickness measurements between the study and control groups in a chronic period. We also noticed that OCTA is a good new noninvasive procedure for imaging choroidal circulation.
Choroidal circulation,OCTA,smoking effect,Optical coherence tomography angiography
https://niles.journals.ekb.eg/article_129168.html
https://niles.journals.ekb.eg/article_129168_a4a351aefa0d9d6830113a52d4250747.pdf
Beni-Suef University, National Institute of Longevity Elderly Sciences
NILES journal for Geriatric and Gerontology
2636-3224
2636-3232
4
Geriatric Ophthalmology
2021
04
01
Evaluation of Corneal biomechanics in primary open angle glaucoma
19
28
EN
Abd elraouf
Abd elghany
Ophthalmology department_benisuif University
raoufomar2013@gmail.com
Hazem
Effat
Haroun
Ophthalmology department, Beni-Suef university
harounhazem@hotmail.com
Safaa
Awadalla
Aboud
Ophthalmology department, Beni-Suef university
dr.safa.aboud123@gmail.com
10.21608/niles.2021.50547.1041
Background: <br />Elevated intraocular pressure (IOP) is one of the most important factors for diagnosis and monitoring of glaucoma. IOP is currently the only modifiable risk factor for glaucoma, cornea is the transparent tissue covering the front of the eye. It is a powerful refracting surface, providing 2/3 of the eye's focusing power. The adult cornea is only about 1/2 millimeter thick and is comprised of 6 layers: epithelium, Bowman's membrane, stroma, Dua's layer, Descemet's membrance and endothelium. <br /><br />Objectives: <br />correlation of Corneal Biomechanics (ORA) with perimetry, IOP and OCT optic nerve results in eyes with primary open angle glaucoma and glaucoma suspect patients. <br /><br />Patients and Methods: <br />This study is a prospective cross-sectional study, ocular response analyzer (ORA) parameters were measured in 40 patients with correlation to their Intraocular pressure (IOP), Perimetry and ocular coherence tomography (OCT) retinal nerve fiber layer thickness (RNFL) on 80 eyes, Patients ages range between 45-65 years old. The study was prepared on patients seeking treatment in ophthalmology polyclinic in The Memorial Institute of Ophthalmic Researches in Giza , they were screened to identify those with primary open angle glaucoma and glaucoma suspect patients. <br /><br />Results:<br />Our study revealed that the corneal biomechanics Parameters are significantly lower in patients with advanced primary open angle glaucoma (POAG). <br /><br />Conclusion: <br />Studying corneal biomechanics is essential for early diagnosis of glaucoma suspect and follow up of primary open angle glaucoma patients.
cornea,Biomechanics,Glaucoma,ORA
https://niles.journals.ekb.eg/article_141054.html
https://niles.journals.ekb.eg/article_141054_adddf25852f24770425c063a3615af67.pdf
Beni-Suef University, National Institute of Longevity Elderly Sciences
NILES journal for Geriatric and Gerontology
2636-3224
2636-3232
4
Geriatric Ophthalmology
2021
04
01
The effect of Capsular rupture and vitreous loss during cataract surgery on Post Operative Visual Acuity
29
38
EN
Shiren
Abd el wahed
Ophthalmology Department , faculty of medicine, Beni Suef university, Beni Suef , Egypt
shirentantawey@yahoo.com
Hazem
Haroun
Ophthalmology Department , faculty of medicine, Beni Suef university, Beni Suef , Egypt
harounhazem@hotmail.com
Abd El Rahman
Shaban
Ahmed
Ophthalmology Department , faculty of medicine, Beni Suef university, Beni Suef , Egypt
dr.a.shaban@gmail.com
10.21608/niles.2021.57498.1044
Abstract <br /> Background: The goal of This study is to determine best corrected visual acuity after catract surgery complicated with capsular rupture and vitreous loss.<br />Methods: This study included 40 subjects had cataract surgeries their ages range from 50 to 65 years divided into 2 groups . The first group included 20 patient whose cataract surgery had no complications ,8 cases(40%) had ECCE and 12 cases(60%) had Phaco,Thier age had mean average +_58.10 and standerd division 4.29. The second group included 20 patient whose cataract surgery complicated with capsular rupture and vitreous loss, 8cases (40%) had ECCE and 12 cases (60%) had phaco,Thier age had mean average +- 58.20 and standerd division 3.69. By measuring BCVA 8 weeks after surgery the BCVA at phaco group the uncomplicated cases had mean +- 0.40 and SD +-0.12 ,the complicated cases had mean +- 0.22 and SD +-0.14.The p value is 0.003 . AT the EXTRA cases ,the uncomplicated cases with mean +|- 0.48 SD +|- 0.29 and the complicated cases had mean +- 0.21 SD +- 0.06 . The p value is 0.033.<br />Results: It was found that BCVA at patients with PCR and vitreous loss is less than other patients whose cataract surgery had no complication .<br />KeyWords:<br />Capsular rupture, vitrous loss, Visual acuity
Capsular rupture,vitrous loss,visual acuity
https://niles.journals.ekb.eg/article_143957.html
https://niles.journals.ekb.eg/article_143957_df2749f16e077c84b3aa56e554ec5724.pdf
Beni-Suef University, National Institute of Longevity Elderly Sciences
NILES journal for Geriatric and Gerontology
2636-3224
2636-3232
4
Geriatric Ophthalmology
2021
04
01
OCT Angiographic changes in diabetic patients after cataract surgery
40
52
EN
Radwa
Sami
Malik
Ophthalmology department - Faculty of Medicine-Beni-Suef University - Beni-Suef - Egypt
radwa.sami89@gmail.com
Hossameldein
Khalil
Ophthalmology department,Faculty of Medicine,Beni-Suef University,Beni-Suef,Egypt
khalil-hossam@hotmail.com
Asmaa
Mohamed
Samir
Ophthalmology department-faculty of Medicine- Beni-Suef University- Beni-Suef- Egypt
m-asmaa@yahoo.com
10.21608/niles.2021.57099.1046
The goal of this prospective non-interventional clinical study was to evaluate the role of OCT-A parameters in determining early changes that occur in DM patients following cataract surgery to be aware about early microvascular changes occurring & when to interfere to prevent complications of DR. The study was carried out on 30 eyes of cataractous diabetic patients without DR & 30 eyes of cataractous non diabetic patients, both underwent phaco. Patients were selected according to inclusion & exclusion criteria then complete ophthalmologic evaluation was done (history, examination and investigations). OCT-A was carried out for study groups before &during follow up after one week, one month &three months after surgery. The study showed that there was a significant increase in foveal & parafoveal thickness after three months in comparison with preoperative values & control group by 12±8.97foveal/ 11.40±3.99 parafoveal(p-value
OCT Angiographiy,cataract surgery,diabetic retinopathy,foveal,Macula
https://niles.journals.ekb.eg/article_148616.html
https://niles.journals.ekb.eg/article_148616_c3b088c2629f96aa9d43c2712211a63e.pdf
Beni-Suef University, National Institute of Longevity Elderly Sciences
NILES journal for Geriatric and Gerontology
2636-3224
2636-3232
4
Geriatric Ophthalmology
2021
04
01
Time Of Maximum Resolution Of Diabetic Macular Oedema After Ranibizumab Injection
53
60
EN
Mohammed
Hassan
0000-0003-2619-7916
Ophthalmology Department , faculty of medicine, Beni Suef university, Beni Suef , Egypt
docto372@gmail.com
Hossam ElDin
Khalil
Ophthalmology Department , faculty of medicine, Beni Suef university, Beni Suef , Egypt
Abd El Rahman
Shaban
Ahmed
Ophthalmology Department , faculty of medicine, Beni Suef university, Beni Suef , Egypt
10.21608/niles.2021.65184.1051
Macular edema is defined as an abnormal thickening of the macula associated with the accumulation of excess fluid in the extracellular space of the neurosensory retina. Intracellular edema involving Müller cells has also been observed histopathologically in some cases.<br /> DME results from retinal microvascular changes, thickening of the basement membrane and reduction in the number of pericytes are believed to lead to increased permeability and incompetence of the retinal vasculature. This compromise of the BRB leads toleakage of plasma constituents into the surrounding retina, with subsequent retinal edema. Hypoxia induced by this mechanism can also stimulate VEGF production. There is evidence that VEGF is up-regulated in DME and proliferative diabetic retinopathy.<br /> Ranibizumab was approved by the FDA in June 2006 for the treatment of all subtypes of neovascular AMD and was approved in 2010 for the treatment of macular edema associated with retinal vein occlusion and diabetic retinopathy.<br />Optical coherence tomography is a non-invasive diagnostic method for the high-resolution imaging of ocular tissues. OCT is very helpful in the diagnosis and follow-up of DME,and OCT also analyzes the vitreomacular relationship.
diabetic,OEDEMA,ranibizumab,macular,Injection
https://niles.journals.ekb.eg/article_157866.html
https://niles.journals.ekb.eg/article_157866_fa96fef2d918ae50cc9a1445d6aea189.pdf
Beni-Suef University, National Institute of Longevity Elderly Sciences
NILES journal for Geriatric and Gerontology
2636-3224
2636-3232
4
Geriatric Ophthalmology
2021
04
01
Refractive Changes After YAG laser Capsulotomy In Pseudophakic Patients
61
67
EN
eman
saeed
fathy
faculty of medicine
eman_asi91@yahoo.com
Hazem
Effat
Haroun
Ophthalmology department, Beni-Suef university
harounhazem@hotmail.com
Ahmed
Taha
Gouda
benisuef opthalmology derpartment
ahmed-oph79@yahoo.com
10.21608/niles.2021.68089.1053
Background: The aim of our study was to evaluate the effect of Nd:YAG laser posterior capsulotomy on patient’s refractive status .<br />Methods: a retrospective study that involved 30 eyes (of 30 patient) treated with Nd:YAG laser capsulotomy due to posterior capsular opacification after uncomplicated phacoemulsification surgery and intraocular lens implantation. Complete ocular examinations were done for all patients before and after YAG capsulotomy. The best corrected visual acuity , sphere and cylinder were obtained before capsulotomy ,one week and one month after capsulotomy and changes were investigated. Data was analyzed statistically. <br />Results: It was found that The mean refractive sphere shift towards myopic changing , The mean refractive cylinder changes towards hyperopic shift , there were no statistical significance of any change in axis of the cylinder .<br />Conclusion: Statistical significant improvement in BCVA after Nd:YAG laser capsulotomy, so Nd:YAG is an effective instrument used in non-invasive treatment of posterior capsular opacification.<br />Keywords <br />Refractive changes after YAG laser capsulotomy in pseudophakic patients .
Refractive,changes,YAG,Laser,Capsulotomy
https://niles.journals.ekb.eg/article_177495.html
https://niles.journals.ekb.eg/article_177495_c9f6785949ac4e23181aaa7fa9684f44.pdf
Beni-Suef University, National Institute of Longevity Elderly Sciences
NILES journal for Geriatric and Gerontology
2636-3224
2636-3232
4
Geriatric Ophthalmology
2021
04
01
Corneal asphericity changes after implantation of intracorneal ring segment (kerarings) in the treatment of Keratoconus
68
77
EN
Rasha
Mohamed
Mousa
0000-0002-9816-506X
Memorial Institute for Ophthalmic Research ,Giza ,Egypt
10.21608/niles.2021.205502
<strong>Purpose: </strong>To evaluate changes in visual outcome, refractive error and corneal asphericity after implantation of intracorneal ring segments (ICRS) (keraring) for the treatment of keratoconus<br /><strong>Setting:</strong> Memorial institute for ophthalmic research, Egypt<br /><strong>Methods</strong>: This study was conducted on 23 eyes of 17 patients with keratoconus. ICRS was implanted intrastromally in the cornea as a treatment for keratoconus. One or two rings with thicknesses ranging from 150 µm to 300 µm and arc lengths ranging from 160<sup>o</sup> to 210<sup>o</sup> were implanted. Uncorrected visual acuity (UCVA),best corrected visual acuity (BCVA)and refractive error (sphere, cylinder)changes were assessed. Keratometric values (k1,K2,Kmax)and corneal asphericity values anterior and posterior respectively(Q ant and Q post ) were obtained from Pentacam .<br /><strong>Results:</strong> There was clinically significant improvement regarding UCVA from 0.1±0.04 to 0.31±0.17 and improvement in BCVA was from 0.37±0.15 to 0.46±0.1. The spherical and cylindrical errors significantly decreased postoperatively (p < 0.001). K2 showed a highly significant decrease (p =0.001) while K1 showed a significant reduction (p=0.022) and Kmax showed non-significant changes postoperatively with p=0.469.Q anterior shows significant decrease from -1.29±0.55 to -0.78±0.77 (p < 0.001) while Q posterior shows non-significant change (p =0.692).<br /><strong>Conclusion:</strong> ICRS implantation for the treatment of keratoconus changes the anterior corneal asphericity by approximating the Q value to the ideal Q value (-0.46) and improves the UCVA and BCVA of patients in addition to decreasing the refractive sphere and cylinder values.<br /><br /><strong> </strong>
intracorneal ring segment,ICRS,Kerarings,Keratoconus
https://niles.journals.ekb.eg/article_205502.html
https://niles.journals.ekb.eg/article_205502_92ad4f2caa7c63cc15f2960a9c2ceb43.pdf