Efficacy of the traditional use of Olive Leaves decoction as Anti-diabetic Agent in Geriatrics.

Document Type : Original Article


1 Biochemistry Department, Faculty of Agriculture Beni-Suef University, Beni-Suef, Egypt.

2 Department of Elderly Nutrition - National Institute of Longevity Elderly Sciences. Beni-Suef University, Beni-Suef, Egypt.

3 Department of Clinical Pharmacy, Faculty of Pharmacy. October 6 University, 6 th October City, Egypt

4 Department of Pharmacognosy, Faculty of Pharmacy, October 6 University, 6 th October City, Egypt

5 Department of Clinical Pharmacy, Faulty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

6 Department of internal medicine, Faculty of Medicine. Beni-Suef University, Beni-Suef, Egypt.


Background: Several studies focused the light on the antidiabetic effect of Olive Leaves extract especially on the geriatrics. Aim : The current study was conducted to evaluate the anti-diabetic effect of olive leaves decoction on elder patients. Methods: The elderly subjects were randomized into 4 groups: Group I: Normal control group , Group II (gp2): hypertensive group, Group III: diabetic group & Group IV : diabetic hypertensive group. Each group included 20 subjects who was taken a specific dose of Olive leaves tea for 8 weeks treatment twice daily with a meal. Blood glucose level was measured at baseline screening and after each week until the end of the study. Results: During the study period, blood sugar and glycosylated hemoglobin changed significantly. The mean fasting blood glucose (F. BL. G.) difference reached up to 11.35 mg/dL for group I ,up to 10.55 mg/dL for Gp. II,  up to 96.70 mg/dL for the Gp. III and up to 78.50 mg/dL for Gp.IV . After 8 weeks of treatment, the mean blood sugar had significantly decreased in group II  and group IV ( p < 0.001; n = 20). Conclusion: the results of this study suggest that olive leaves extract is beneficial to the diabetic patients to control plasma glucose level.